Key result
Regional echo intensity correlated with myocardial collagen content in patients with chronic left ventricular disease, indicating collagen is a major determinant of echo intensity.
Why the study?
Does regional echo intensity correlate with myocardial connective tissue in patients with chronic left ventricular disease?
Population
20 patients with chronic left ventricular disease who had cross-sectional echocardiograms recorded within…
Comparison
Measurement of regional echo amplitude from… vs Histological and biochemical assessment of…
Design
Cross-sectional
Follow-up
within one week of death
Authors
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May support non-invasive fibrosis assessment by echo in chronic LV disease; leaves open prospective validation before practice change.
Cross-Sectional (n=20)
Does regional echo intensity correlate with myocardial connective tissue in patients with chronic left ventricular disease?
In chronic left ventricular disease, myocardial collagen content appears to be the major determinant of regional echo intensity, suggesting echocardiography can non-invasively assess myocardial fibrosis.
Shaw et al. (1984) conducted a cross-sectional in Chronic left ventricular disease (n=20). Regional echo intensity was evaluated on Correlation between regional echo intensity and myocardial collagen content. Regional echo intensity correlated with myocardial collagen content in patients with chronic left ventricular disease, indicating collagen is a major determinant of echo intensity.
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