Key result
Antihypertensive therapy achieves systolic BP targets in ~60% of multimorbid outpatients despite poor diastolic control.
Why the study?
Arterial hypertension is highly prevalent and tied to cardiovascular risk across age groups, but the adequacy of antihypertensive therapy in outpatient multimorbid patients across different age groups required assessment.
What is the adequacy of antihypertensive therapy and the frequency of achieving target blood pressure levels in outpatient multimorbid patients with arterial hypertension?
Observational (n=323)
What is the adequacy of antihypertensive therapy and the frequency of achieving target blood pressure levels in outpatient multimorbid patients with arterial hypertension?
In multimorbid outpatients with arterial hypertension, target systolic blood pressure is achieved in 60% of cases, but diastolic control remains poor at 22%, highlighting the need for optimized combination therapy.
Inadequate diastolic control in multimorbid outpatients warrants caution; leaves open optimization in prospective trials.
Introduction . Arterial hypertension (AH) is the most common chronic non-communicable disease, especially among individuals over 60 years old, where its prevalence exceeds 60%. The relationship between blood pressure (BP) levels and the risk of cardiovascular events is observed across all age groups. The aim of the study was to assess the adequacy of antihypertensive therapy in outpatient multimorbid patients of different age groups. Materials and methods . The study included 323 outpatient patients with verified AH (92 men and 231 women). Patients were divided into three age groups: middle-aged, elderly, and old age. The frequency of achieving target BP levels, the structure of antihypertensive therapy, and the prescription of lipid-lowering and antiplatelet agents were evaluated. Results . The severity of AH did not differ between the groups. In the elderly groups, patients with high cardiovascular risk and comorbidities such as type 2 diabetes and osteoarthritis predominated. The most frequently prescribed medications were inhibitors of the renin-angiotensin-aldosterone system (94.1%). Target BP levels were mainly achieved due to systolic pressure (60%), while diastolic pressure was only controlled in 22% of cases. Discussion . The results are consistent with previous studies. Conclusion . AH in elderly patients is associated with high comorbidity and cardiovascular risk. Achieving target BP levels is possible with combination therapy, including renin-angiotensin-aldosterone system blockers and calcium antagonists. Additional treatment strategies are needed to reduce the residual risk of cardiovascular diseases.
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Изможерова et al. (2025) conducted an observational in Arterial hypertension (n=323). Antihypertensive therapy was evaluated on Frequency of achieving target blood pressure levels. Antihypertensive therapy in outpatient multimorbid patients achieved target systolic blood pressure in 60% of cases, whereas target diastolic pressure was controlled in only 22%.
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