Key result
Sex, racial, and ethnic disparities in ACS presentation and management contribute to worse clinical outcomes.
This review highlights the importance of recognizing demographic disparities and novel risk factors in acute coronary syndromes to improve early diagnosis and clinical outcomes.
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Alerts clinicians to demographic ACS disparities; leaves open whether targeted interventions narrow outcome gaps.
In this review, sex, racial, and ethnic differences in acute coronary syndromes on a global scale are summarized. The relationship between disparities in presentation and management of acute coronary syndromes and effect on worse clinical outcomes in acute coronary syndromes are discussed. The effect of demographic, geographic, racial, and ethnic factors on acute coronary syndrome care disparities are reviewed. Differences in risk factors including systemic inflammatory disorders and pregnancy-related factors and the pathophysiology underlying them are discussed. Finally, breast arterial calcification and coronary calcium scoring are discussed as methods to detect subclinical atherosclerosis and start early treatment in an attempt to prevent clinical disease.
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Khraishah et al. (2023) conducted a review in Acute Coronary Syndrome. Sex, racial, and ethnic disparities in acute coronary syndrome presentation and management contribute to worse clinical outcomes, emphasizing the need for early detection and treatment.
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