Key result
AF ablation improves LVEF and reduces mortality and HF hospitalizations vs medical therapy.
Why the study?
AF and heart failure commonly coexist, and recent evidence suggested AF ablation might improve LVEF, mortality, and heart failure hospitalisations, prompting a more detailed analysis.
Does left atrial ablation improve left ventricular ejection fraction and reduce death and heart failure hospitalisation in patients with concomitant atrial fibrillation and heart failure?
Systematic Review
Does left atrial ablation improve left ventricular ejection fraction and reduce death and heart failure hospitalisation in patients with concomitant atrial fibrillation and heart failure?
This systematic review aims to assess the utility of atrial fibrillation ablation as a non-pharmacological treatment for patients with concomitant heart failure.
Answers are grounded in this paper and cite their sources.
Supports ablation over medical therapy for atrial fibrillation in heart failure; confirms mortality and hospitalization benefits in Level 1 evidence.
AF and heart failure (HF) commonly coexist. Left atrial ablation is an effective treatment to maintain sinus rhythm (SR) in patients with AF. Recent evidence suggests that the use of ablation for AF in patients with HF is associated with an improved left ventricular ejection fraction and lower death and HF hospitalisation rates. We performed a systematic search of world literature to analyse the association in more detail and to assess the utility of AF ablation as a non-pharmacological tool in the treatment of patients with concomitant HF.
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Eysenck et al. (2020) conducted a systematic review in Atrial Fibrillation and Heart Failure. Catheter ablation vs. Medical therapy or rate control was evaluated. Catheter ablation for atrial fibrillation in patients with heart failure improves left ventricular ejection fraction and reduces mortality and heart failure hospitalizations compared to medical therapy.
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