Key result
Vaccinated dairy cattle show ~22% FMD virus seroprevalence, indicating ongoing infection risk.
Why the study?
Foot-and-mouth disease is endemic in Iran, and the study investigated the prevalence of antibodies against 3ABC non-structural protein of the virus in vaccinated dairy cattle.
Cross-Sectional (n=283)
Yes
The presence of NSP antibodies in vaccinated dairy cattle in Kurdistan Province indicates a risk of infection with circulating FMD virus serotypes.
Suggests FMD circulation risk in vaccinated herds; hypothesis-generating for targeted surveillance before practice changes.
Foot-and-mouth disease (FMD), a highly contagious viral disease of livestock, is endemic in Iran. To investigate the prevalence of antibodies against 3ABC non-structural protein (NSP) of FMD virus, a cross-sectional study was conducted on dairy cattle in eight cities of Kurdistan Province from May to September 2016. Serum samples (n = 283), were collected from cattle vaccinated with the recommended dose of a commercial vaccine and tested by a Competition enzyme-linked immunosorbent assay. Results showed the overall seroprevalence of antibodies against NSP of FMD virus in the vaccinated cattle was 22.30% (95.00% CI: 17.40 - 27.20%). The seroprevalence of antibodies was affected by geographical regions, with the highest seroprevalence related to the samples of vaccinated cattle in the cities of Marivan 95.00% (95.00% CI: 92.50 - 97.50%) and Saqqez 38.50% (95.00% CI: 32.80 - 44.20%). In terms of age, the highest seroprevalence of antibodies to FMD virus 26.70% (95.00% CI: 21.60-31.80%) belonged to ≤ 24-month-old cattle. These findings suggest that the presence of NSP antibodies in vaccinated cattle indicates the risk of infection with FMD virus serotypes circulating in the west of the province, so further studies with a larger sample size are recommended.
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Azimi et al. (2023) conducted a cross-sectional in Foot-and-mouth disease (n=283). Commercial FMD vaccine was evaluated on Seroprevalence of antibodies against 3ABC non-structural protein (NSP) of FMD virus (95% CI 17.40 - 27.20%). The overall seroprevalence of antibodies against the non-structural protein of FMD virus in vaccinated dairy cattle was 22.30% (95% CI: 17.40-27.20%), indicating a risk of infection.
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