Why the study?
Does chronic smoking impair baroreceptor function and alter autonomic nervous blood pressure regulation compared to non-smokers?
Population
54 individuals, comprising 24 smokers who smoked >10 cigarettes per day for >6 years, and 30 non-smokers.
Comparison
Chronic smoking vs Non-smokers
Design
Cross-sectional
Follow-up
24 hours
Authors
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May underlie increased CV risk in smokers; extends acute data to chronic 24-h effects but remains hypothesis-generating.
Does chronic smoking impair baroreceptor function and alter autonomic nervous blood pressure regulation compared to non-smokers?
Chronic smoking is associated with sympathovagal imbalance and decreased baroreceptor sensitivity, which may contribute to the increased cardiovascular risk in smokers.
Gerhardt et al. (1999) studied this question.
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