Key result
Smoking significantly decreased baroreflex sensitivity from 15.4 to 11.2 ms/mmHg (P<0.05) and increased mean arterial blood pressure and heart rate.
Why the study?
Does smoking four cigarettes within one hour impair baroreflex sensitivity in humans?
Population
Humans (demographics and sample size not specified in abstract)
Comparison
Smoking (four cigarettes within one hour) vs Baseline (pre-smoking)
Design
Other
Follow-up
30 minutes post-smoking
Authors
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Acute autonomic effects of smoking merit further study; leaves open implications for hypertension in Level 5 evidence.
Observational
Does smoking four cigarettes within one hour impair baroreflex sensitivity in humans?
Absolute Event Rate: 11.2% vs 15.4%
p-value: p=<0.05
Acute smoking significantly impairs baroreflex sensitivity and increases sympathetic activity, highlighting a physiological mechanism by which tobacco abuse increases cardiovascular risk.
Gerhardt et al. (1999) reported an observational. Smoking vs. Baseline (pre-smoking) was evaluated on Baroreflex sensitivity (p=<0.05). Smoking significantly decreased baroreflex sensitivity from 15.4 to 11.2 ms/mmHg (P<0.05) and increased mean arterial blood pressure and heart rate.
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