Key result
Pulmonary vein antrum isolation as a primary ablation strategy achieved 5-year freedom from atrial tachyarrhythmia in 58.3% of patients, with additional substrate modification adding moderate benefit.
Why the study?
Does pulmonary vein antrum isolation improve long-term sinus rhythm maintenance in patients with atrial fibrillation?
Population
509 consecutive patients with atrial fibrillation (mean age 57 years, 38.9% non-paroxysmal AF)
Design
Cohort
Follow-up
Mean 66 ± 23 months after first ablation and 55 ± 25…
Authors
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Supports PVAI for long-term AF rhythm control in observational cohorts; leaves open randomized comparisons to medical therapy.
Cohort (n=509)
No
Does pulmonary vein antrum isolation improve long-term sinus rhythm maintenance in patients with atrial fibrillation?
PVAI as a primary ablation strategy provides long-term freedom from atrial tachyarrhythmia in the majority of patients, with substrate modification offering only modest additional benefit while increasing the risk of atypical flutter.
Teunissen et al. (2016) conducted a cohort in Atrial fibrillation (n=509). Pulmonary vein antrum isolation (PVAI) was evaluated on Long-term freedom from atrial tachyarrhythmia. Pulmonary vein antrum isolation as a primary ablation strategy achieved 5-year freedom from atrial tachyarrhythmia in 58.3% of patients, with additional substrate modification adding moderate benefit.
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