This paper reviews the physiological and pathophysiological mechanisms of contraction in the normal and failing heart.
Offers mechanistic synthesis for heart failure care; leaves open targeted therapeutic translation.
THE function of the heart is to propel unoxygenated blood to the lungs and to deliver oxygenated blood to the peripheral tissues in accordance with their metabolic requirements. Since William Harve...
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Braunwald et al. (1976) studied this question.
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