Key result
Patient-specific modeling of cardiac electrophysiology using reaction-diffusion models successfully reproduced measured ECGs and activation orders in two heart failure patients with LBBB.
Why the study?
Can patient-specific modelling of cardiac electrophysiology reproduce measured ECGs and electrograms in heart-failure patients with LBBB?
Can patient-specific modelling of cardiac electrophysiology reproduce measured ECGs and electrograms in heart-failure patients with LBBB?
Tuning a reaction-diffusion model of the human heart to reproduce measured ECGs and electrograms is feasible and may provide insights into individual disease characteristics.
No takes yet. Share an insight, caveat, or question.
Supports feasibility in small HF cohorts with LBBB; leaves open clinical utility and needs larger validation.
Potse et al. (2014) studied Heart failure with left bundle-branch block (n=2). Patient-specific modelling of cardiac electrophysiology was evaluated on Reproduction of measured ECGs and cardiac electrograms. Patient-specific modeling of cardiac electrophysiology using reaction-diffusion models successfully reproduced measured ECGs and activation orders in two heart failure patients with LBBB.
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