Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 24, 2026Microbiology SpectrumOpen Access

Schiff base-assisted catalytic fabrication of TiO 2 nanoparticles for antibacterial applications against multidrug-resistant strains

View Full Paper
Ask AI
Bookmark
Share

Authors

FBFarasat BibiKohat University of Science and TechnologyABAhtaram BibiKohat University of Science and TechnologyNKNaila KhalidKohat University of Science and Technology

Discussion

Loading...

Member takes

Overview

Randomized trial shows enhanced antibacterial effects of TiO2 nanoparticles in multidrug-resistant bacteria, suggesting new treatment options.

Key Points

  • The study aims to develop titanium dioxide nanoparticles with improved antibacterial properties against multidrug-resistant bacteria using Schiff base complexes.
  • Synthesis of TiO2 nanoparticles via sol-gel method using Schiff base as catalyst
  • Characterization using UV-visible spectroscopy, FTIR, SEM, and XRD to confirm nanoparticle formation
  • Assessment of antibacterial activity against MDR strains using well diffusion method.
  • TiO2 nanoparticles exhibited significant antibacterial effects, with NP2 showing the largest zones of inhibition against tested strains.
  • MIC and MBC assays confirmed NP2's superiority, particularly against Staphylococcus aureus, with the lowest inhibitory and bactericidal concentrations.
  • The Schiff base modification improved the effectiveness of TiO2 nanoparticles against resistant pathogens.

Cite This Study

Bibi et al. (2026) studied this question.

synapsesocial.com/papers/6a12959d48a0ea1665671be0https://doi.org/10.1128/spectrum.02641-25
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bacterial synthesis parameters and antibacterial mechanisms of titanium dioxide nanoparticles against multidrug resistant Gram-negative pathogens2026
  2. 2Tapping into the Power of Sol-Gel Method for Enhanced Antimicrobial Activity of Titania Nanoparticles2024 · 3 citations
  3. 3Electron Microscope Scanning, and Antibacterial Activity of Tio2 Nanoparticles on pathogenic strains of Staphylococcus aureus and Escherichia coli2024
  4. 4Preparation of Titanium Dioxide Nanoparticles (Tio2 Nps) using the Sol-Gel Method and their Photocatalytic Antibacterial Activity Against Multidrug-Resistant Bacteria2026
  5. 5Sol–Gel-Derived TiO<sub>2</sub> and TiO<sub>2</sub>/Cu Nanoparticles: Synthesis, Characterization, and Antibacterial Efficacy2024 · 61 citations