Key result
Valve-in-valve JenaValve Trilogy TAVR successfully treats severe regurgitation in a failing stentless bioprosthesis.
Why the study?
There were no existing reports on the use of dedicated TAVR devices to treat regurgitation caused by structural valve deterioration of a stentless bioprosthesis.
Can a dedicated transcatheter valve be successfully used to treat pure regurgitation in a failing stentless bioprosthesis?
Case Report (n=1)
No
Can a dedicated transcatheter valve be successfully used to treat pure regurgitation in a failing stentless bioprosthesis?
A dedicated transcatheter valve (JenaValve Trilogy System) can be successfully used for valve-in-valve TAVR to treat pure regurgitation in a failing stentless bioprosthesis.
Demonstrates feasibility of dedicated TAVR for valve-in-valve pure AR; leaves open durability, safety, and efficacy in larger cohorts.
BACKGROUND: An 80-year-old man presented with progressive dyspnea due to severe isolated regurgitation of a 29-mm ATS 3f stentless (model 1000) aortic bioprosthesis. Because of his advanced age and multiple severe comorbidities, the Heart Team opted for a valve-in-valve transcatheter aortic valve replacement (TAVR). CASE SUMMARY: Based on preprocedural computed tomography planning, a valve-in-valve TAVR procedure was successfully performed via transfemoral access using a 27-mm JenaValve Trilogy System. DISCUSSION: Although the use of dedicated TAVR devices for the treatment of native aortic regurgitation has been well-described, to our knowledge, there are no existing reports on their use to address regurgitation caused by the structural valve deterioration of a stentless bioprosthesis. TAKE-HOME MESSAGE: Consider a dedicated transcatheter valve to treat pure regurgitation in a failing stentless bioprosthesis.
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Corona et al. (2026) conducted a case report in Severe isolated regurgitation of a stentless aortic bioprosthesis (n=1). Valve-in-valve transcatheter aortic valve replacement (TAVR) using a 27-mm JenaValve Trilogy System was evaluated on Procedural success. A valve-in-valve TAVR procedure using a 27-mm JenaValve Trilogy System was successfully performed to treat severe isolated regurgitation in a failing stentless bioprosthesis in an 80-year-old man.
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