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May 24, 2026MedicineOpen Access

Impact of sarcopenia on postoperative outcomes and recurrence in patients with Crohn disease: A retrospective cohort study

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Authors

GYGun‐Hee YiJLJong Lyul LeeKKKyung Won Kim

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Overview

Retrospective cohort study evaluates sarcopenia's effect on surgical outcomes in Crohn disease patients, suggesting risk stratification benefits.

Key Points

  • This study aims to evaluate the effect of preoperative and postoperative sarcopenia on outcomes in Crohn disease patients undergoing surgery.
  • Retrospective cohort design with data from January 2006 to December 2016
  • Included 569 patients who underwent abdominal surgery for Crohn disease
  • Used computed tomography to calculate skeletal muscle index for sarcopenia assessment
  • 412 patients (72.4%) had preoperative sarcopenia, identified as an independent risk factor for complications (RR = 1.88, 95% CI: 1.00–3.53; P = .049)
  • 58.2% of patients with sarcopenia at diagnosis still had it postoperatively
  • Post-SG had significantly lower 5-year surgical recurrence-free survival (88.7% ± 2.1% vs 93.8% ± 1.5%, P = .019)

Cite This Study

Yi et al. (2026) studied this question.

synapsesocial.com/papers/6a12965848a0ea1665673097https://doi.org/10.1097/md.0000000000048930
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sarcopenia As a Determinant Prognostic Factor After Surgery Among Patients with Colorectal Cancer2024
  2. 2Prevalence of preoperative sarcopenia according to EWGSOP2 in patients with colorectal cancer and its impact on surgical outcomes: a prospective observational study2026
  3. 3Sarcopenia predicts poor long-term survival but not postoperative complications in gastric cancer surgery: an 18-year retrospective cohort study2025 · 3 citations
  4. 4Prognostic Significance of Sarcopenia in Colorectal Cancer: A Review of Clinical Evidence2026 · 1 citations
  5. 5Obesity, Sarcopenia and Myosteatosis: Impact on Clinical Outcomes in the Operative Management of Crohn’s Disease2023 · 21 citations