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June 13, 2026BMC SurgeryOpen Access

Prevalence of preoperative sarcopenia according to EWGSOP2 in patients with colorectal cancer and its impact on surgical outcomes: a prospective observational study

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Authors

MYMustafa YılmazMBMahsum BarçinSTSimge Tuna

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Overview

Observational study evaluates sarcopenia's role in postoperative outcomes in colorectal cancer patients, highlighting its implications.

Key Points

  • This study aims to investigate the prevalence of sarcopenia based on EWGSOP2 criteria and its effect on short-term surgical outcomes in colorectal cancer patients.
  • Conducted a prospective observational study with 70 consecutive colorectal cancer patients undergoing curative surgery.
  • Assessed muscle strength via handgrip strength, physical performance through 4-m gait speed, and muscle mass using L3 CT skeletal muscle index.
  • Classified patients into non-sarcopenic and varying stages of sarcopenia according to the EWGSOP2 guidelines.
  • 41 (58.6%) patients were non-sarcopenic; 29 (41.4%) had at least probable sarcopenia, with increased major complications (probable 34.4%, confirmed 37.0%, severe 55.5%) vs. 9.7% in non-sarcopenic.
  • Length of hospital stay was longer for those with sarcopenia (9.3-10.6 days) compared to non-sarcopenic (6.1 days; p < 0.001).
  • At least probable sarcopenia was linked to major complications (aOR 11.75, 95% CI 1.27–108.82; p = 0.030) and extended hospital stay (aOR 8.33, 95% CI 1.01–68.38; p = 0.049).

Cite This Study

Yılmaz et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf528faef96ed7f057379https://doi.org/10.1186/s12893-026-03935-8
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