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May 1, 2026HLA

Characterisation of the Novel HLA‐A*03:535 Allele by Next Generation Sequencing and Oxford Nanopore Sequencing

Jarret Merschman Rachel Barnes Justin Kreuter Laurie Wakefield Manish J. Gandhi

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Key Points

The aim is to characterize the novel HLA-A*03:535 allele and understand its genetic implications.
Characterization was performed through next generation sequencing and Oxford Nanopore sequencing techniques.
Analysis focused on the nucleotide substitution in exon 1.
The HLA-A*03:535 allele features a single nucleotide substitution in exon 1.

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Implication

Characterizes the novel HLA-A*03:535 allele, suggesting a new understanding of genetic variation.

Abstract

The novel HLA-A*03:535 allele is characterised by a single nucleotide substitution in exon 1.

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Cite This Study

Merschman et al. (2026) studied this question.

synapsesocial.com/papers/6a12968148a0ea16656734f0 https://doi.org/10.1111/tan.70761

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Characterisation of the Novel <i>HLA‐A*03:01:140</i> Allele by Sequencing‐Based TypingOriginal Research · 2026 · 1 citations
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4Characterisation of the Novel <i>HLA‐A*23:23:02</i> Allele by Next Generation Sequencing2025 · 2 citations
5Characterisation of the Novel <i>HLA‐DQB1*06:03:58</i> Allele by Next‐Generation SequencingOriginal Research · 2026 · 1 citations

Characterisation of the Novel <i>HLA‐A*26:268</i> Allele by Next Generation Sequencing2026
Characterisation of the Novel <i>HLA‐DQA1*03:02:05</i> Allele by Next‐Generation Sequencing2025
Characterisation of the Novel <i>HLA‐C*03:741</i> Allele by Next Generation Sequencing2026
Identification of the Novel HLA‐B*35:670 Allele by Next‐Generation Sequencing in a Bone Marrow DonorHLA · 2026
Description of the Novel HLA‐C*06:414 Allele in a Bone Marrow DonorHLA · 2026

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