What question did this study set out to answer?

To determine whether comorbid type 2 diabetes mellitus delays functional recovery, impairs neuroplasticity, and worsens quality of life following stroke.

January 1, 2020Journal of Family Medicine and Primary CareOpen Access

Diabetes mellitus type 2 impedes functional recovery, neuroplasticity and quality of life after stroke

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To determine whether comorbid type 2 diabetes mellitus delays functional recovery, impairs neuroplasticity, and worsens quality of life following stroke.
Evaluated 208 stroke patients grouped by the presence (group 1) or absence (group 2) of type 2 diabetes mellitus.
Assessed baseline severity using the Glasgow Coma Scale and NIH Stroke Scale, functional improvement via the Functional Independence Measure, and quality of life via the Stroke Specific Quality of Life Scale.
Quantified neuroplasticity by measuring serum levels of brain-derived neurotrophic factor (BDNF).
Diabetic patients had significantly higher risks of poor functional recovery on the Functional Independence Measure (RR 1.34, 95% CI 1.0–1.8; OR 1.8, 95% CI 1.03–3.12).
Type 2 diabetes independently predicted poor BDNF recovery (serum BDNF < 10.07 ± 3.8 ng/mL) with an RR of 2.40 (95% CI 1.36–4.21) and an OR of 1.6 (95% CI 1.15–2.13).
Patients with diabetes experienced significantly worse quality-of-life outcomes (RR 1.56, 95% CI 1.13–2.16; OR 2.83, 95% CI 1.14–7.0).

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Implication

Cohort study reveals type 2 diabetes impairs functional recovery, neuroplasticity, and quality of life after stroke, highlighting metabolic disease as a key barrier to neurological rehabilitation.

Cite This Study

Chaturvedi et al. (2020) studied this question.

synapsesocial.com/papers/6a12affec031bb6829a71a07 https://doi.org/10.4103/jfmpc.jfmpc_884_19

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Implication

Cohort study reveals type 2 diabetes impairs functional recovery, neuroplasticity, and quality of life after stroke, highlighting metabolic disease as a key barrier to neurological rehabilitation.

Diabetes mellitus type 2 impedes functional recovery, neuroplasticity and quality of life after stroke

Key Points

Discussion

Implication

Cite This Study

Diabetes mellitus type 2 impedes functional recovery, neuroplasticity and quality of life after stroke

Key Points

Discussion

Implication

Cite This Study

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