Key result
A model using vitals, FBG, activity, and lipid therapy predicts poor 36-month outcomes with ~70% sensitivity.
Why the study?
The determinants of long-term outcomes beyond the acute phase in ischemic stroke patients comorbid with type 2 diabetes mellitus are not adequately known.
Population
624 ischemic stroke patients with type 2 diabetes treated with conservative measures
Comparison
Patients with poor outcome (mRS ≥3) vs good outcome (mRS <3)
Design
Prospective nested case–control study
Follow-up
36 months
Authors
Loading...
May refine prognostic models in diabetic IS; leaves open whether identified determinants guide targeted interventions.
Case-Control (n=624)
Pulse rate at admission, diastolic blood pressure, fasting blood glucose, physical activity, and lipid-lowering therapy are key determinants of long-term prognosis in patients with ischemic stroke and comorbid type 2 diabetes.
Liu et al. (2022) conducted a case-control in Ischemic stroke comorbid with type 2 diabetes mellitus (n=624). Clinical and laboratory risk factors (pulse rate, DBP, FBG, physical activity, lipid-lowering treatment) was evaluated on Poor outcome (modified Rankin Scale score ≥3) at 36 months. A forecasting model using pulse rate, DBP, FBG, physical activity, and lipid-lowering treatment distinguished good versus poor outcomes with 70.1% sensitivity and 73.5% specificity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: