Key result
Vascular and endothelial cellular stiffness contribute to atherosclerotic lesion formation by altering endothelial cell functions and promoting monocyte and macrophage adhesion.
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Design
Review
Does not inform clinical management of atherosclerosis; leaves open whether targeting endothelial stiffness improves outcomes.
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Takayuki Okamoto (2019) studied this question. Vascular and endothelial cellular stiffness contribute to atherosclerotic lesion formation by altering endothelial cell functions and promoting monocyte and macrophage adhesion.
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