September 15, 1996Circulation
Transcatheter Subendocardial Infusion
Why the study?
Does transcatheter subendocardial infusion effectively map and ablate ventricular myocardium?
Population
Ventricular myocardium (n=62 infusions: 14 mapping, 48 ablation)
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Supports feasibility of infusion-based mapping and ablation in animals; leaves open translation to human ventricular tachycardia.
Structured PICO
Does transcatheter subendocardial infusion effectively map and ablate ventricular myocardium?
P
Population
Ventricular myocardium (n=62 infusions: 14 mapping, 48 ablation)
I
Intervention
Transcatheter subendocardial infusion of mapping injectant (lidocaine, iohexal, glycerin) or ablation injectant (ethanol, iohexal, glycerin) via a needle-tipped deflectable electrode catheter
O
Outcome
Fluoroscopic stain, local capture threshold, and lesion volumesurrogate
Transcatheter subendocardial infusion is a feasible technique for mapping and ablating ventricular myocardium, producing predictable lesion volumes.
Cite This Study
Goette et al. (1996) studied this question.