Key result
No clinical trial data was provided in the text, only the journal's editorial board information.
Why the study?
Does a single 60 mg oral dose of DU-176b reduce ex-vivo thrombus formation compared to baseline in healthy subjects?
Population
12 healthy subjects
Comparison
Single 60 mg oral dose of DU-176b vs Baseline (pre-dose)
Design
Cohort
Follow-up
12 hours
Authors
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No trial data extracted; leaves open whether DU-176b reduces ex-vivo thrombus formation.
Does a single 60 mg oral dose of DU-176b reduce ex-vivo thrombus formation compared to baseline in healthy subjects?
A single 60 mg oral dose of the direct factor Xa inhibitor DU-176b significantly reduced ex-vivo thrombus formation and thrombin generation in healthy subjects up to 5 hours post-dose.
Zafar et al. (2007) studied this question. DU-176b was evaluated. No clinical trial data was provided in the text, only the journal's editorial board information.
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