Key result
HIV infection in France was associated with an increased risk of myocardial infarction compared to the general population, with an overall standardized morbidity ratio of 1.5 (95% CI 1.3-1.7).
Why the study?
Does HIV infection increase the risk of myocardial infarction compared to the general population in France?
Cohort
Does HIV infection increase the risk of myocardial infarction compared to the general population in France?
Effect estimate: Standardized morbidity ratio 1.5 (95% CI 1.3-1.7)
HIV-infected patients in France have a significantly higher risk of myocardial infarction compared to the general population, with a particularly pronounced relative risk in women.
May warrant heightened MI vigilance in HIV care; extends observational data but leaves causal and interventional questions open.
The incidence of myocardial infarction (MI) is lower in France than in English-speaking and northern European countries. We estimated the incidence of MI in the HIV-infected population in France, on the basis of the data from the FHDH-ANRS CO4 cohort, by comparison with the general population. The sex- and age-standardized morbidity ratio was estimated as 1.5 [95% confidence interval (CI) 1.3-1.7] overall, 1.4 (95% CI 1.3-1.6) in men and 2.7 (95% CI 1.8-3.9) in women.
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Lang et al. (2010) conducted a cohort in HIV infection. HIV infection vs. General population was evaluated on Incidence of myocardial infarction (Standardized morbidity ratio 1.5, 95% CI 1.3-1.7). HIV infection in France was associated with an increased risk of myocardial infarction compared to the general population, with an overall standardized morbidity ratio of 1.5 (95% CI 1.3-1.7).
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