Why the study?
Do virological and immunological parameters (HIV replication, CD4 nadir, CD8 count) predict the risk of myocardial infarction in HIV-infected individuals?
Population
1,173 HIV-infected individuals from the French Hospital Database on HIV, including 289 cases with a…
Comparison
Plasma HIV-1 RNA levels >50 copies/mL, low CD4… vs HIV-infected individuals without myocardial…
Design
Case-control
Authors
Loading...
May inform CV risk stratification in HIV; hypothesis-generating for targeted interventions.
Do virological and immunological parameters (HIV replication, CD4 nadir, CD8 count) predict the risk of myocardial infarction in HIV-infected individuals?
HIV replication, low CD4 T-cell nadir, and high CD8 T-cell count are independent predictors of myocardial infarction in HIV-infected individuals, highlighting the role of immune status and viral load in cardiovascular risk.
Lang et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: