Population
Isolated cat papillary muscles and left atrial strips
Design
Preclinical
Authors
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No immediate change to clinical inotrope selection; leaves open translation of active-state framework to human myocardium.
This study provides a framework for characterizing inotropic stimuli based on their distinct effects on the intensity and duration of the active state in cardiac muscle.
Buccino et al. (1967) studied this question.
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