Key result
A 1-day increase in weight telemonitoring adherence is linked to ~19% lower mortality and fewer hospitalizations.
Why the study?
Adherence to telemonitoring may be associated with heart failure exacerbation but is not included in telemonitoring algorithms.
Is adherence to weight telemonitoring associated with a reduced risk of hospitalization, emergency department visit, or death in patients recently hospitalized for decompensated heart failure?
RCT (n=538)
Yes
Is adherence to weight telemonitoring associated with a reduced risk of hospitalization, emergency department visit, or death in patients recently hospitalized for decompensated heart failure?
Lower adherence to weight telemonitoring is associated with an increased short-term risk of hospitalization or death, indicating that adherence behavior may serve as a marker of a patient's underlying health status.
Adherence may flag near-term risk after HF hospitalization; leaves open whether interventions targeting adherence improve outcomes.
Importance: Adherence to telemonitoring may be associated with heart failure exacerbation but is not included in telemonitoring algorithms. Objective: To assess whether telemonitoring adherence is associated with a patient's risk of hospitalization, emergency department visit, or death. Design, Setting, and Participants: This post hoc secondary analysis of the Better Effectiveness After Transition-Heart Failure randomized clinical trial included patients from 6 academic medical centers in California who were eligible if they were hospitalized for decompensated heart failure and excluded if they were discharged to a skilled nursing facility, were expected to improve because of a medical procedure, or did not have the cognitive or physical ability to participate. The trial compared a telemonitoring intervention with usual care for patients with heart failure after hospital discharge from October 12, 2011, to September 30, 2013. Data analysis was performed from November 8, 2016, to May 10, 2019. Interventions: The intervention group (n = 722) received heart failure education, telephone check-ins, and a wireless telemonitoring system that allowed the patient to transmit weight, blood pressure, heart rate, and selected symptoms. The control group (n = 715) received usual care. Patients were followed up for 180 days after discharge. Main Outcomes and Measures: The main outcome was within-person risk of hospitalization, emergency department visit, or death by week during the study period. Poisson regression was used to determine the within-person association of adherence to daily weighing with the risk of experiencing these events in the following week. Results: Among the 538 participants (mean [SD] age, 70.9 [14.1] years; 287 [53.8%] male; 269 [50.7%] white) in the present analysis, adherence was lowest during the first week after enrollment but steadily increased, peaking between days 26 and 60 at 69%, or 371 transmissions. Adherence to weight telemonitoring was associated with events in the following week; an increase in adherence by 1 day was associated with a 19% decrease in the rate of death in the following week (incidence rate ratio, 0.81; 95% CI, 0.73-0.90) and an 11% decrease in the rate of hospitalization (incidence rate ratio, 0.89; 95% CI, 0.86-0.91). Adherence in the previous week was not associated with reduced rates of emergency department visits (incidence rate ratio, 0.95; 95% CI, 0.90-1.02). Conclusions and Relevance: In this study, lower adherence to weight telemonitoring in a given week was associated with an increased risk of subsequent hospitalization or death in the following week. It is unlikely that this is a result of the telemonitoring intervention; rather, adherence may be an important factor associated with a patient's health status.
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Haynes et al. (2020) conducted an RCT in decompensated heart failure (n=538). Weight telemonitoring vs. Usual care was evaluated on within-person risk of hospitalization, emergency department visit, or death by week (IRR 0.81 for death, IRR 0.89 for hospitalization, 95% CI 0.73-0.90 for death, 0.86-0.91 for hospitalization). A 1-day increase in weight telemonitoring adherence was associated with decreased rates of death (IRR 0.81; 95% CI 0.73-0.90) and hospitalization (IRR 0.89; 95% CI 0.86-0.91) in the following week.
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