Observational study demonstrates high reproducibility of paired cardiac output measurements in patients with cardiopulmonary disorders, supporting the clinical reliability of the Fick principle.
Two determinations of cardiac output using the Fick principle were performed within a 15 min. time period in a series of 167 patients representing a wide spectrum of cardiac and pulmonary disorders. The reproducibility of the 2 readings was found to be satisfactory, attesting to the reliability of the practical application of the Fick principle as employed in clinical medicine.
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Selzer et al. (1958) studied this question.
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