Population
Patients with a failing heart
Design
Review
Authors
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Supports ACE inhibitor use in heart failure; leaves open validation of energy balance mechanisms.
The paper highlights the theoretical framework that vasodilators (like ACE inhibitors) and negative inotropic agents improve heart failure prognosis by restoring the balance between energy production and utilization.
Arnold M. Katz (1991) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: