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January 1, 2013Journal of the Korean Society of HypertensionOpen Access

In women, increased left atrial volume index was significantly associated with early systolic blood pressure elevation during exercise (R2 = 0.192, p = 0.002), whereas pulse wave velocity showed no association.

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Why the study?

Is early systolic blood pressure response to exercise associated with left atrial volume index and pulse wave velocity?

Population

205 patients (137 men and 68 women; mean age 58 ± 11 years; range, 19 to 83 years)

Design

Cross-sectional

Key result

In women, increased left atrial volume index was significantly associated with early systolic blood pressure elevation during exercise (R2 = 0.192, p = 0.002), whereas pulse wave velocity showed no association.

Authors

JPJae Ho ParkSJSeon‐Ah JinYLYoung-Dal Lee

Discussion

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Member takes

Overview

Suggests sex-specific exercise BP-LA remodeling link in women; hypothesis-generating and should not yet alter practice.

Study Design

Type

Observational (n=205)

Multicenter

No

Structured PICO

Is early systolic blood pressure response to exercise associated with left atrial volume index and pulse wave velocity?

P
Population
205 patients (137 men and 68 women; mean age 58 ± 11 years; range, 19 to 83 years)
I
Intervention
Graded exercise test (BRUCE protocol)
O
Outcome
Association of early systolic blood pressure response to exercise (delta SBP) with left atrial volume index (LAVI) and brachial ankle pulse wave velocity (PWV)surrogate

Main Result

Effect estimate: R2 = 0.192

p-value: p=0.002

Early systolic blood pressure elevation during exercise is associated with increased left atrial volume index in women, suggesting a sex-specific relationship between exercise hemodynamics and left atrial remodeling.

Limitations

  • Heterogeneous study population with various underlying diseases, including hypertension.
  • Retrospective study design limited the ability to assess past exercise capacity.
  • Exercise stress test, pulse wave velocity, and echocardiography were not performed simultaneously.
  • Significantly lower maximal heart rate in patients with ischemic heart disease may have limited the analysis.

Cite This Study

Park et al. (2013) conducted an observational in Chest pain or chest discomfort (n=205). Graded exercise test (BRUCE protocol) was evaluated on Association between early systolic blood pressure response to exercise (delta SBP1) and left atrial volume index (LAVI) in women (R2 = 0.192, p=0.002). In women, increased left atrial volume index was significantly associated with early systolic blood pressure elevation during exercise (R2 = 0.192, p = 0.002), whereas pulse wave velocity showed no association.

synapsesocial.com/papers/6a130928011838bad99e30dbhttps://doi.org/10.5646/jksh.2013.19.2.45
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