Key result
Endothelial vasodilator function independently correlated with the difference between resting and maximal pulse pressure during exercise in men (R2=0.17, P<0.03) and women (R2=0.12, P<0.03).
Population
82 adults, aged 55 to 75 years, with untreated high normal blood pressure or mild hypertension but otherwise…
Design
Cross-sectional
Authors
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Endothelial function correlates with exercise BP response; hypothesis-generating and requires longitudinal validation before clinical use.
Cross-Sectional (n=82)
Impaired endothelial vasodilator function, measured by flow-mediated vasodilation, is independently associated with exaggerated exercise blood pressure responses, particularly in men with high normal BP or mild hypertension.
Kerry J. Stewart (2004) conducted a cross-sectional in Untreated high normal blood pressure or mild hypertension (n=82). Treadmill exercise was evaluated on Relationship of endothelial vasodilator function (FMD) and aortic stiffness (PWV) with exercise blood pressure. Endothelial vasodilator function independently correlated with the difference between resting and maximal pulse pressure during exercise in men (R2=0.17, P<0.03) and women (R2=0.12, P<0.03).