Key result
Point-of-care testing for cardiac markers significantly reduced the mean time to baseline results compared with local laboratory testing (2.1 vs 2.5 hours, P<0.01) with similar diagnostic accuracy.
Why the study?
Does point-of-care testing for myoglobin and cTnT reduce time to results without loss of diagnostic accuracy compared to standard laboratory testing in ED patients with suspected non-ST-elevation ACS?
Observational (n=223)
Does point-of-care testing for myoglobin and cTnT reduce time to results without loss of diagnostic accuracy compared to standard laboratory testing in ED patients with suspected non-ST-elevation ACS?
Absolute Event Rate: 2.1% vs 2.5%
p-value: p=< 0.01
Point-of-care multimarker testing in the ED significantly reduces time to cardiac marker results without compromising diagnostic accuracy for ACS compared to central laboratory testing.
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Supports POC cardiac testing to shorten ED result times in suspected ACS; leaves open need for RCTs on outcomes before practice change.
Storrow et al. (2006) conducted an observational in Suspected acute coronary syndrome without ST-segment elevation (n=223). Point-of-care (POC) testing for myoglobin and cardiac troponin T vs. Standard-of-care local laboratory (LL) tests for CK-MB and cTnT was evaluated on Time from presentation to baseline marker result (p=< 0.01). Point-of-care testing for cardiac markers significantly reduced the mean time to baseline results compared with local laboratory testing (2.1 vs 2.5 hours, P<0.01) with similar diagnostic accuracy.
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