Key result
Tissue Doppler imaging assessment of combined systolic and diastolic left ventricular dysfunction independently predicted death in the general population (HR 2.5 for third vs first tertile; P<0.005).
Why the study?
Does cardiac dysfunction assessed by Tissue Doppler Imaging predict mortality in the general population?
Population
1036 participants from the Copenhagen City Heart Study, a community-based population study
Comparison
Tissue Doppler imaging evaluating peak systolic… vs Conventional echocardiography and clinical…
Design
Cohort
Follow-up
median 5.3 years
Authors
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Supports TDI for mortality risk stratification in general populations; hypothesis-generating and requires prospective validation before clinical adoption.
Cohort (n=1,036)
Does cardiac dysfunction assessed by Tissue Doppler Imaging predict mortality in the general population?
Effect estimate: HR 2.5
p-value: p=<0.005
Tissue Doppler imaging is a powerful and independent predictor of mortality in the general population, particularly when combining systolic and diastolic performance indices.
Møgelvang et al. (2009) conducted a cohort in General population (n=1,036). Tissue Doppler imaging (TDI) vs. Conventional echocardiography was evaluated on Death (HR 2.5, p=<0.005). Tissue Doppler imaging assessment of combined systolic and diastolic left ventricular dysfunction independently predicted death in the general population (HR 2.5 for third vs first tertile; P<0.005).
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