Key result
C-reactive protein and fibrinogen levels in healthy obese subjects showed no significant relationship with systolic or diastolic blood pressure (rho -0.057 to 0.068; P>0.13).
Why the study?
Is there a relationship between markers of inflammation (CRP, fibrinogen) and blood pressure or other hemodynamic variables in healthy obese subjects?
Population
487 obese subjects from the general population, free of major cardiovascular diseases, not taking…
Design
Cross-sectional
Authors
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No link to BP in healthy obesity does not support inflammation as direct mediator; leaves open causal pathways for longitudinal study.
Cross-Sectional (n=487)
Is there a relationship between markers of inflammation (CRP, fibrinogen) and blood pressure or other hemodynamic variables in healthy obese subjects?
Effect estimate: rho -0.057 to 0.068
p-value: p=>0.13
In healthy obese subjects, inflammatory markers (CRP and fibrinogen) do not correlate with blood pressure, suggesting that inflammation may not directly mediate obesity-related hypertension.
Asferg et al. (2009) conducted a cross-sectional in Obesity (n=487). C-reactive protein and fibrinogen was evaluated on Relationship with systolic BP, diastolic BP, pulse pressure, or ankle brachial index (rho -0.057 to 0.068, p=>0.13). C-reactive protein and fibrinogen levels in healthy obese subjects showed no significant relationship with systolic or diastolic blood pressure (rho -0.057 to 0.068; P>0.13).
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