Key result
Early cardiac rehabilitation is linked to ~30% lower 90-day mortality in dilated cardiomyopathy versus delayed care.
Why the study?
Cardiac rehabilitation is an established cardiovascular treatment, but the outcomes of early cardiac rehabilitation in patients with dilated cardiomyopathy remain underexplored.
Does early cardiac rehabilitation reduce 90-day mortality in patients with dilated cardiomyopathy and symptomatic heart failure?
Population
30,296 patients with DCM and symptomatic heart failure in Japan
Comparison
Early CR (within 3 days of admission) vs delayed or no CR
Design
National inpatient database propensity score matching study
Follow-up
90 days
Authors
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Should not yet change practice in dilated cardiomyopathy; leaves open whether RCTs confirm causal benefit.
Cohort (n=30,296)
Yes
Does early cardiac rehabilitation reduce 90-day mortality in patients with dilated cardiomyopathy and symptomatic heart failure?
Effect estimate: OR 0.70 (95% CI 0.53-0.93)
Absolute Event Rate: 4.1% vs 5.8%
p-value: p=0.01
Early initiation of cardiac rehabilitation within 3 days of admission is associated with reduced 90-day mortality and improved activities of daily living scores at discharge in patients with dilated cardiomyopathy and symptomatic heart failure.
Yasufuku et al. (2025) conducted a cohort in Dilated cardiomyopathy and symptomatic heart failure (n=30,296). Early cardiac rehabilitation vs. Delayed or no cardiac rehabilitation was evaluated on 90-day mortality (OR 0.70, 95% CI 0.53-0.93, p=0.01). Early cardiac rehabilitation initiated within 3 days of admission significantly reduced 90-day mortality (OR 0.70) compared to delayed or no cardiac rehabilitation in patients with dilated cardiomyopathy.
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