Key result
Indirect comparison of tenecteplase versus reteplase in patients with acute myocardial infarction showed no significant difference in the risk of mortality (OR 0.98, p > 0.05).
Why the study?
Does tenecteplase have similar efficacy and safety compared to reteplase in patients with acute myocardial infarction?
Meta-Analysis (n=49,875)
Does tenecteplase have similar efficacy and safety compared to reteplase in patients with acute myocardial infarction?
Answers are grounded in this paper and cite their sources.
Tenecteplase and reteplase demonstrate similar efficacy and safety in acute myocardial infarction based on indirect comparison, suggesting the choice depends on price and accessibility.
). Indirect comparison suggests similar efficacy and safety of tenecteplase and reteplase. Hence, the use of each one of the two medicines depends on price, facility, and accessibility of the medicine.
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Zia-Behbahani et al. (2019) conducted a meta-analysis in Acute myocardial infarction (n=49,875). Tenecteplase vs. Reteplase was evaluated on Mortality (OR 0.98, p=>0.05). Indirect comparison of tenecteplase versus reteplase in patients with acute myocardial infarction showed no significant difference in the risk of mortality (OR 0.98, p > 0.05).
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