Key result
High-sensitivity cardiac troponin I concentrations (median 8.4 ng/L in men, 5.3 ng/L in women) were significantly associated with incident CVD, CHD, and all-cause death over up to 10 years.
Why the study?
Does high-sensitivity cardiac troponin I (hs-cTnI) predict cardiovascular events and mortality in older community dwellers?
Population
5764 older community dwellers (age 66-98 years, 2416 men and 3275 women) from the AGES-Reykjavik cohort
Design
Cohort
Follow-up
up to 10 years
Authors
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hs-cTnI may aid risk stratification in older adults; leaves open incremental value over standard predictors.
Cohort (n=5,764)
Does high-sensitivity cardiac troponin I (hs-cTnI) predict cardiovascular events and mortality in older community dwellers?
High-sensitivity cardiac troponin I is a strong, independent predictor of cardiovascular events and mortality in older community-dwelling individuals, even at concentrations below the 99th percentile.
Þorsteinsdóttir et al. (2016) conducted a cohort in Older community dwellers (n=5,764). High-sensitivity cardiac troponin I (hs-cTnI) was evaluated on All-cause death and incidence of cardiovascular disease (CVD) and coronary heart disease (CHD). High-sensitivity cardiac troponin I concentrations (median 8.4 ng/L in men, 5.3 ng/L in women) were significantly associated with incident CVD, CHD, and all-cause death over up to 10 years.
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