Key result
Cardiac troponin I levels predict ~44% higher all-cause mortality in elderly community dwellers.
Why the study?
Cardiac troponin levels are often detectable in community dwellers using sensitive assays, but information on their course over time and prognostic implications is limited.
Do high-sensitive cardiac troponin I levels predict mortality in elderly community dwellers?
Cohort (n=1,004)
Do high-sensitive cardiac troponin I levels predict mortality in elderly community dwellers?
Hazard Ratio: 1.44 (95% CI 1.18–1.77)
High-sensitive cardiac troponin I levels are detectable in most elderly individuals, increase over time, and independently predict all-cause and cardiovascular mortality.
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May refine mortality risk stratification in elderly outpatients; hypothesis-generating for randomized trials.
Eggers et al. (2013) conducted a cohort in Elderly community dwellers (n=1,004). Cardiac troponin I (cTnI) levels was evaluated on All-cause mortality (HR 1.44, 95% CI 1.18 to 1.77). Cardiac troponin I levels independently predicted all-cause mortality (adjusted HR 1.44; 95% CI 1.18 to 1.77) and increased over time in elderly community dwellers.
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