Key result
Recurrent SCAD in a male athlete prompts DAPT discontinuation 4 years after initial event.
Why the study?
Spontaneous coronary artery dissection is rare in male patients, particularly with recurrence, and data on the best treatment in men are limited.
Case Report (n=1)
Highlights a rare case of recurrent SCAD in a middle-aged male athlete and discusses the clinical decision to discontinue DAPT to avoid exacerbating intramural bleeding.
Late recurrent SCAD in male athlete may warrant DAPT reevaluation; extends sparse male data but leaves optimal therapy open.
BACKGROUND: Spontaneous coronary artery dissection (SCAD) is a rare condition, mainly affecting young women. Cases in male patients are rare, especially with recurrence. CASE SUMMARY: A 59-year-old male non-elite athlete presented as an ST-elevation myocardial infarction following a 5-km run. Urgent coronary angiogram was normal, but cardiac magnetic resonance showed a myocardial infarction. Four years later, he experienced similar chest pain with no ST-elevation on electrocardiogram and a mild troponin rise. Urgent coronary angiogram was initially thought normal but subsequent close inspection confirmed a Type 2b SCAD. Cardiac magnetic resonance showed a small additional myocardial infarction contained within an area of acute myocardial oedema. DISCUSSION: Spontaneous coronary artery dissection is more common in young women compared to men and recurrent dissection has been rarely reported in the literature. Cohort studies have shown the rate of recurrent dissection to be 13-16%, but most of the patients in these cohorts are female. Poor data exists on the best treatment of SCAD in men, but given the presence of intramural thrombus, dual antiplatelet therapy was discontinued on the presumption that it may exacerbate an intramural bleeding process.
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Fitzpatrick et al. (2020) conducted a case report in Spontaneous coronary artery dissection (SCAD) (n=1). Discontinuation of dual antiplatelet therapy was evaluated. A 59-year-old male athlete experienced recurrent spontaneous coronary artery dissection 4 years after an initial event, prompting discontinuation of dual antiplatelet therapy.
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