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May 25, 2026Journal of Integrative AgricultureOpen Access

Genesis and biological features of H7 avian influenza viruses in migratory birds and implications for cross-species infection

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Authors

JSJinyan ShenLLLili LiuZ1Zhang, Nan, 1966-

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Overview

Randomized trial characterizes H7 avian influenza viruses in migratory birds, highlighting pandemic risks.

Key Points

  • This research aims to characterize the H7 avian influenza viruses circulating in migratory birds to assess their pandemic potential.
  • Characterization of H7N2 and H7N4 viruses in migratory birds from eastern China from 2017 to 2024.
  • Examination of viral replication and shedding in domestic birds like ducks and chickens.
  • Analysis of genetic mutations in mouse models to evaluate virulence and adaptation.
  • H7 viruses were primarily found in Anatidae, Phasianidae, and Scolopacidae species and displayed significant genetic diversity.
  • H7N2 and H7N4 viruses infected domestic birds, showing replication and shedding, with specific mutation impacts on virulence.
  • Rapid emergence of mammalian-adapted mutants was observed in mice, with key substitutions enhancing replication and stability.

Cite This Study

Shen et al. (2026) studied this question.

synapsesocial.com/papers/6a13e71a0e02ee3982d31e27https://doi.org/10.1016/j.jia.2026.05.019
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