Key result
Biomarkers including natriuretic peptides, collagen synthesis markers, CRP, galectin-3, and CT-apelin show promising results for predicting left ventricular remodeling and response to cardiac resynchronization therapy.
Why the study?
Although cardiac resynchronization therapy improves symptoms and decreases mortality in heart failure, some patients do not respond properly to treatment.
Can biomarkers predict response to cardiac resynchronization therapy in patients with heart failure?
Design
Review
Authors
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May aid CRT response prediction in HF; hypothesis-generating and requires prospective validation before practice change.
Can biomarkers predict response to cardiac resynchronization therapy in patients with heart failure?
Various biomarkers, including BNP and CRP, show promise in predicting which heart failure patients will respond favorably to cardiac resynchronization therapy, though more research is needed.
Asgardoon et al. (2019) conducted a review in Heart Failure. Biomarkers (e.g., natriuretic peptides, collagen synthesis markers, CRP, galectin-3, CT-apelin) was evaluated on Prediction of response to Cardiac Resynchronization Therapy (CRT). Biomarkers including natriuretic peptides, collagen synthesis markers, CRP, galectin-3, and CT-apelin show promising results for predicting left ventricular remodeling and response to cardiac resynchronization therapy.
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