Key result
SAPIEN 3 valve achieves procedural success and clinical improvement in high-risk patients with challenging anatomies.
Why the study?
Transcatheter aortic valve replacement devices are increasingly applied in high-risk scenarios and nonaortic settings, but procedural adaptations for these complex cases require detailed description.
Case Report (n=5)
No
The SAPIEN 3 transcatheter heart valve can be successfully deployed in high-risk scenarios with anatomic challenges or for tricuspid valve-in-valve implantation when appropriate technical adjustments are made.
Answers are grounded in this paper and cite their sources.
May support feasibility in select high-risk anatomies; hypothesis-generating and should not yet alter practice.
The transcatheter aortic valve replacement procedure is used in patients with aortic stenosis. Transcatheter aortic valve replacement devices are quite versatile; thus, they are increasingly being used for nonaortic applications, such as tricuspid valve-in-valve implantation. This case series describes a transcatheter aortic valve replacement procedure in 4 patients with anatomic challenges (eg, aortic tortuosity, high valvular calcium burden, highly calcified bicuspid valve, low coronary artery takeoff, left main coronary artery occlusion, and large aortic annulus) and a fifth patient who had a failed tricuspid bioprosthesis and underwent a tricuspid valve-in-valve implantation with the Edwards SAPIEN 3 transcatheter heart valve (Edwards Lifesciences). All procedures required adjustments to the standard protocol, and each procedure was successful. The critical, technical adjustments in the deployment technique and preprocedural planning of the procedures are detailed to provide a road map for other cardiologists who encounter similar challenges.
No takes yet. Share an insight, caveat, or question.
Nascimbene et al. (2022) conducted a case report in Severe aortic stenosis and degenerated tricuspid bioprosthesis (n=5). Edwards SAPIEN 3 transcatheter heart valve was evaluated on Procedural success. The Edwards SAPIEN 3 transcatheter heart valve was successfully deployed in five high-risk patients with challenging anatomies, resulting in procedural success and clinical improvement.
Synapse has enriched 10 related papers. Consider them for comparative context: