December 18, 2007JAMA
“False-Positive” Cardiac Catheterization Laboratory Activation Among Patients With Suspected ST-Segment Elevation Myocardial Infarction
Key result
False-positive cardiac catheterization laboratory activation occurred in 14% (95% CI 12.2-16.0%) of patients with suspected STEMI, based on the absence of a culprit coronary artery.
Population
1345 patients with suspected STEMI transferred from 30 community and rural hospitals with pretransfer…
Design
Cohort
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
False-positive STEMI activations warrant caution in activation decisions; leaves open the efficacy of improved triage algorithms.
Study Design
Type
Observational (n=1,345)
Multicenter
Yes
Structured PICO
P
Population
1345 patients with suspected STEMI transferred from 30 community and rural hospitals with pretransfer catheterization laboratory activation for percutaneous coronary intervention at a tertiary cardiovascular center in Minnesota
I
Intervention
Pretransfer cardiac catheterization laboratory activation for suspected STEMI
O
Outcome
Prevalence of false-positive catheterization laboratory activation by 3 criteria: no culprit coronary artery, no significant coronary artery disease, and negative cardiac biomarker resultssurrogate
False-positive cardiac catheterization laboratory activation for suspected STEMI is relatively common, occurring in approximately 9% to 14% of cases depending on the definition used.
Cite This Study
Larson et al. (2007) conducted an observational in Suspected ST-Segment Elevation Myocardial Infarction (STEMI) (n=1,345). Pretransfer cardiac catheterization laboratory activation was evaluated on Prevalence of false-positive catheterization laboratory activation (no culprit coronary artery) (95% CI 12.2-16.0). False-positive cardiac catheterization laboratory activation occurred in 14% (95% CI 12.2-16.0%) of patients with suspected STEMI, based on the absence of a culprit coronary artery.