Key result
High-risk pregnant women developing complications had lower stress-corrected midwall shortening at 24 weeks' gestation than those with uncomplicated outcomes (77.9% vs 107.9%, P<0.001).
Why the study?
Are left ventricular midwall mechanics altered in high-risk normotensive pregnant women who develop placenta-related complications compared to those with uncomplicated pregnancies?
Cohort (n=172)
Are left ventricular midwall mechanics altered in high-risk normotensive pregnant women who develop placenta-related complications compared to those with uncomplicated pregnancies?
Absolute Event Rate: 107.9% vs 77.9%
p-value: p=<0.001
Maternal left ventricular midwall mechanics are depressed during pregnancy and postpartum in high-risk normotensive women who develop placenta-related complications.
No takes yet. Share an insight, caveat, or question.
Depressed midwall shortening at 24 weeks may flag high-risk pregnancies; leaves open whether LV mechanics predict placenta-related complications.
Novelli et al. (2011) conducted a cohort in High-risk normotensive pregnancy (n=172). Uncomplicated pregnancy outcome vs. Complicated pregnancy outcome was evaluated on Stress-corrected midwall shortening (SCmFS%) at 24 weeks' gestation (p=<0.001). High-risk pregnant women developing complications had lower stress-corrected midwall shortening at 24 weeks' gestation than those with uncomplicated outcomes (77.9% vs 107.9%, P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: