Key result
Echocardiographic EDV index cut-offs for 2DE/RT3DE >87/104 ml/m2 identified severe aortic regurgitation (PLR 5.0/5.0), and >69/87 ml/m2 identified severe mitral regurgitation (PLR 14.9/5.5).
Why the study?
What are the echocardiographic cut-off values for left ventricular dimensions that indicate severe chronic aortic or mitral regurgitation compared to CMR?
Observational (n=83)
What are the echocardiographic cut-off values for left ventricular dimensions that indicate severe chronic aortic or mitral regurgitation compared to CMR?
Echocardiographic left ventricular volume index cut-offs can reliably identify severe chronic aortic and mitral regurgitation, outperforming linear dimensions.
Volume cut-offs may aid echo grading of severe AR/MR; leaves open prospective outcome validation versus CMR.
Objectives Cut-off values for left ventricular (LV) dimensions indicating severe valve regurgitation have not been defined. The aim of this study was to establish echocardiographic cut-off values for LV dimensions indicating severe chronic aortic (AR) or mitral (MR) regurgitation. Design The hemodynamic significance was confirmed by documented reduction of end-diastolic volume (EDV) and symptom relief after surgery. Eighty-three patients with moderate or severe regurgitation (AR, n = 41; MR, n = 42) without other cardiac conditions underwent prospectively two-dimensional (2DE), real-time three-dimensional (RT3DE) echocardiography and cardiovascular magnetic resonance (CMR) exams within 4 h. Results The relationship between EDVCMR and EDV2DE and EDVRT3DE were strong (R 0.95 and 0.91). EDV index cut-offs for 2DE/RT3DE >87/104 ml/m(2) identified AR patients with severe regurgitation with a positive likelihood ratio (PLR) of 5.0/5.0. The corresponding in patients with MR EDV index cut-offs were >69/87 ml/m(2) with a PLR of 14.9/5.5. LV linear dimensions could not identify patients with severe regurgitation. Conclusions LV volumes by echocardiography can support the diagnosis of severe chronic regurgitation. Importantly, other causes for LV enlargement have to be considered.
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Bech‐Hanssen et al. (2016) conducted an observational in Chronic aortic and mitral regurgitations (n=83). Two-dimensional (2DE) and real-time three-dimensional (RT3DE) echocardiography vs. Cardiovascular magnetic resonance (CMR) was evaluated on Echocardiographic cut-off values for left ventricular dimensions indicating severe chronic aortic or mitral regurgitation. Echocardiographic EDV index cut-offs for 2DE/RT3DE >87/104 ml/m2 identified severe aortic regurgitation (PLR 5.0/5.0), and >69/87 ml/m2 identified severe mitral regurgitation (PLR 14.9/5.5).
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