Key result
Unattended SPRINT-like blood pressure measurements (139.77/75.42 mm Hg) were similar to conventional clinic measurements with no statistically significant difference (P=0.163).
Why the study?
Does unattended automated office BP measurement differ from conventional clinic BP measurement in high-risk hypertensive patients?
RCT (n=65)
No
Does unattended automated office BP measurement differ from conventional clinic BP measurement in high-risk hypertensive patients?
p-value: p=0.163
Unattended automated office blood pressure measurements yield similar results to conventional attended clinic measurements, supporting the validity of the SPRINT trial's BP measurement methodology.
Supports SPRINT BP targets in routine hypertension care; confirms unattended and attended measurements are equivalent.
Results of the SPRINT study have been disputed, based on the assumption that unattended BP measurements do not correlate with usual BP measurements. In this study, the authors investigated the correlation of unattended SPRINT‐like measurements with other conventional measurements. All BP measurements were taken with the patient seated in a comfortable chair with the legs uncrossed and not speaking during the procedure. For the purpose of this study, sixty‐five patients, mostly male (93%), were recruited from our hypertension clinic and all were on antihypertensive medication (av 3.0 ± 1.1). Patients were at high cardiovascular risk with high rates of comorbidities, av age 68 ± 12 years, 49% with diabetes, 34% with mild CKD (CKD 1‐3, average eGFR 55.0 ± 13 mL/min/1.73 m 2 ), and 20% with history of stable coronary artery disease. All BP measurements were similar with no statistically significant difference (one‐way ANOVA, P = 0.621). Compared to unattended SPRINT BP values (139.77 ± 19.22/75.42 ± 11.72 mm Hg), the clinic BP measurements were numerically slightly higher but with a NS P value ( P = 0.163). Similarly, unattended BP measurements were similar to values taken by the clinic physician. In a smaller cohort of 11 patients, the authors compared unobserved vs observed SPRINT‐like BP measurements, and in 13 patients, the authors compared unobserved SPRINT‐like BP measurements to average home BP measurements (Table 3). There were no significant differences between any of the subgroups (one‐way ANOVA, P = 0.816 for systolic and P = 0.803 for diastolic). The authors conclude that unattended BP measurements taken (the SPRINT way) are similar to other conventional office blood pressure measurements.
No takes yet. Share an insight, caveat, or question.
Papademetriou et al. (2018) conducted an RCT in Hypertension (n=65). Unattended SPRINT-like BP measurements vs. Conventional clinic BP measurements was evaluated on Difference between unattended SPRINT-like BP measurements and conventional clinic BP measurements (p=0.163). Unattended SPRINT-like blood pressure measurements (139.77/75.42 mm Hg) were similar to conventional clinic measurements with no statistically significant difference (P=0.163).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: