Influence of aging on Doppler echocardiographic indices of left ventricular diastolic function.
Key result
Aging independently alters left ventricular diastolic function indices, significantly increasing maximal late diastolic flow velocity (r=0.69) and decreasing the early-to-late ratio (r=-0.63).
Why the study?
Does aging influence Doppler echocardiographic indices of left ventricular diastolic function in normal volunteers?
Population
86 normal volunteers aged from 20 to 74 years (mean 36)
Comparison
Aging vs Comparison among different age groups
Design
Cross-sectional
Authors
Discussion
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Implication
Supports age-adjusted echo norms for diastolic grading; leaves open links to clinical outcomes in older adults.
Study Design
Type
Cross-Sectional (n=86)
Structured PICO
Does aging influence Doppler echocardiographic indices of left ventricular diastolic function in normal volunteers?
P
Population
86 normal volunteers aged from 20 to 74 years (mean 36)
I
Intervention
Aging (observational assessment across different age groups)
C
Comparator
Comparison among different age groups (20 to 29 years, 30 to 49 years, and 50 to 74 years)
O
Outcome
Six Doppler echocardiographic indices of left ventricular diastolic functionsurrogate
Aging independently affects Doppler echocardiographic indices of left ventricular diastolic function, highlighting the need for age-adjusted normal limits.
Cite This Study
Spirito et al. (1988) conducted a cross-sectional in Normal volunteers (n=86). Age was evaluated on Doppler echocardiographic indices of left ventricular diastolic function. Aging independently alters left ventricular diastolic function indices, significantly increasing maximal late diastolic flow velocity (r=0.69) and decreasing the early-to-late ratio (r=-0.63).