Key result
Coronary wall MRI detected greater maximum coronary wall thickness in asymptomatic individuals with ≥2 cardiovascular risk factors compared to those with ≤1 risk factor (2.59 vs. 2.36 mm, P=0.05).
Why the study?
Does coronary wall MRI detect increased coronary wall thickness in asymptomatic individuals with subclinical markers of atherosclerotic disease?
Population
38 asymptomatic participants of the Multi-Ethnic Study of Atherosclerosis study, free of clinical…
Design
Cross-sectional
Authors
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Supports coronary wall MRI for subclinical atherosclerosis assessment; leaves open its prognostic value and clinical utility pending prospective validation.
Cross-Sectional (n=38)
Does coronary wall MRI detect increased coronary wall thickness in asymptomatic individuals with subclinical markers of atherosclerotic disease?
Absolute Event Rate: 2.59% vs 2.36%
p-value: p=0.05
Coronary artery wall MRI can detect increased coronary wall thickness in asymptomatic individuals, even those with a zero calcium score, correlating with other subclinical markers of atherosclerosis.
Macedo et al. (2008) conducted a cross-sectional in Asymptomatic individuals free of clinical cardiovascular disease (n=38). Coronary wall magnetic resonance imaging (MRI) vs. Computed tomography calcium score, carotid intimal-medial thickness, and risk factors was evaluated on Maximum coronary wall thickness (p=0.05). Coronary wall MRI detected greater maximum coronary wall thickness in asymptomatic individuals with ≥2 cardiovascular risk factors compared to those with ≤1 risk factor (2.59 vs. 2.36 mm, P=0.05).
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