Key result
Significant coronary artery disease was present in 45.7% of valvular disease patients with angina versus 19.2% without angina (P<0.001), but prevalence was only 3% when both were absent.
Why the study?
Does the absence of angina and coronary risk factors reliably exclude significant coronary artery disease in patients undergoing valve replacement?
Population
387 consecutive patients with valvular heart disease undergoing routine coronary arteriography prior to…
Design
Cohort
Authors
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Absence of angina and risk factors linked to low CAD prevalence in valve patients; leaves open whether angiography can be safely omitted pending prospective data.
Observational (n=387)
Does the absence of angina and coronary risk factors reliably exclude significant coronary artery disease in patients undergoing valve replacement?
Absolute Event Rate: 45.7% vs 19.2%
p-value: p=<0.001
Preoperative coronary arteriography might be safely omitted in patients undergoing valve replacement who have neither angina nor coronary risk factors due to a very low prevalence of significant coronary artery disease.
Ramsdale et al. (1984) conducted an observational in Valvular heart disease (n=387). Angina and coronary risk factors vs. Absence of angina and coronary risk factors was evaluated on Significant coronary artery disease (p=<0.001). Significant coronary artery disease was present in 45.7% of valvular disease patients with angina versus 19.2% without angina (P<0.001), but prevalence was only 3% when both were absent.
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