Key result
Routine use of rotavirus vaccines in national programs has reduced all-cause diarrhea hospitalizations by 17%-55%, rotavirus hospitalizations by 49%-92%, and all-cause diarrhea deaths by 22%-50%.
Why the study?
Do rotavirus vaccines reduce diarrhea, hospitalizations, and deaths in children?
Population
Children worldwide
Design
Review
Authors
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Supports real-world rotavirus vaccine impact on pediatric diarrhea; leaves open need for controlled trials to confirm durability and equity.
Do rotavirus vaccines reduce diarrhea, hospitalizations, and deaths in children?
Routine use of rotavirus vaccines significantly reduces diarrhea-related hospitalizations and deaths in children, with a highly favorable risk-benefit profile.
Tate et al. (2014) conducted a review in Severe diarrhea caused by rotavirus. Rotavirus vaccines was evaluated on All-cause diarrhea hospitalizations, rotavirus hospitalizations, and all-cause diarrhea deaths. Routine use of rotavirus vaccines in national programs has reduced all-cause diarrhea hospitalizations by 17%-55%, rotavirus hospitalizations by 49%-92%, and all-cause diarrhea deaths by 22%-50%.
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