Key result
CABG in severe heart failure is associated with a 9.5% in-hospital mortality rate.
Why the study?
Coronary artery bypass grafting is historically associated with higher mortality in patients with severe heart failure, prompting an evaluation of in-hospital mortality and associated adverse factors in an Iranian population.
Observational (n=865)
No
In Iranian patients with severe heart failure (LVEF < 35%) undergoing CABG, in-hospital mortality remains high at 9.5%, though off-pump surgery was associated with significantly lower mortality than on-pump surgery.
BACKGROUND: Historically, coronary artery bypass grafting is associated with a higher mortality rate in patients with severe heart failure. This study aimed to assess the in-hospital mortality of CABG in patients with severe heart failure in Iranian patients and to identify factors associated with adverse outcomes. METHODS: This retrospective descriptive study enrolled patients with severe heart failure who underwent coronary artery bypass surgery from 2015 to 2020 in Madani Hospital, affiliated with Tabriz University of Medical Sciences. RESULTS: A total of 865 consecutive patients with a mean age of 60.65 ± 10.00 were enrolled in the study. Of all participants, 175 were female (20.4%), and 684 were male. The overall mortality rate was 9.5%. In the univariate analysis, predictors of ICU mortality were age, female sex, DM, and renal failure (P value < 0.05). None of the factors studied was an independent predictor of ICU mortality in the multivariate analysis. CONCLUSION: This study established that although coronary artery bypass surgery is reported to have low mortality and postoperative morbidity in patients with severe heart failure, there are still centers that face higher mortality rates in these patients. Improving these patients' outcomes would be possible through identifying the associated risk factors and pre-and postoperative management.
No takes yet. Share an insight, caveat, or question.
Khalili et al. (2022) conducted an observational in Severe heart failure (n=865). Coronary artery bypass grafting (CABG) was evaluated on Overall in-hospital mortality. Coronary artery bypass grafting in patients with severe heart failure was associated with an overall in-hospital mortality rate of 9.5%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: