Key result
CABG in severe LV dysfunction carries ~7% hospital mortality, strongly linked to diabetes and renal failure.
Why the study?
To assess in-hospital complications and identify risk factors for adverse outcomes in patients with severe LV dysfunction undergoing CABG.
Observational (n=190)
CABG in patients with severe LV dysfunction has an acceptable overall in-hospital mortality of 7.3%, but comorbid diabetes and renal failure significantly increase mortality risk.
May inform preoperative risk assessment by diabetes and renal failure in severe LV dysfunction; leaves open randomized comparison to medical therapy.
Objective: To assess the in-hospital complications of patients undergoing coronary artery bypass grafting (CABG) with severe LV dysfunction and to recognize the risk factors for adverse outcomes. Methods: This was a prospective descriptive study, containing patients who underwent CABG from 01-June-2019 to 31-Jan-2022 with documented LVEF < 35%. 190 patients for has been selected for this study. Postoperative data in ICU and ward regarding morbidity, mortality, hemorrhage, cardiac arrest, pacemaker implantation, IABP insertion requirement, and discharge data were collected to determine early postoperative outcomes. Results: The study sample enrolled 190 patients with multivessel CAD with severe LV dysfunction (EF <35%), of all patients, 147 were male and 43 female. Post-surgery hemorrhage has been observed in 23 (12.1%) patients, 9 patients were taken for re-exploration. The average ICU stay of 5.1 ± 3.6 days and Overall hospital mortality was 14 (7.3%). Patients with LV dysfunction and diabetes have a high mortality rate (OR 8.66, p-value of 0. 01), which is highly significant. patients with LV dysfunction with renal failure have a significant mortality rate risk (OR 3.85, p-value of 0.014). Conclusion: Our findings that CABG is associated with enhanced survival in multivessel coronary disease with LV dysfunction with low mortality and postoperative morbidity. In patients with LV dysfunction, diabetes and renal failure are important risk factors in decision making.
No takes yet. Share an insight, caveat, or question.
Malik et al. (2022) conducted an observational in Multivessel coronary artery disease with severe left ventricular dysfunction (n=190). Coronary artery bypass grafting (CABG) was evaluated on Overall hospital mortality. CABG in patients with multivessel coronary disease and severe LV dysfunction resulted in 7.3% hospital mortality, with diabetes (OR 8.66) and renal failure (OR 3.85) identified as major risk factors.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: