Why the study?
Does oral amiodarone treatment alter exercise hemodynamics and left ventricular relaxation in patients with hypertrophic cardiomyopathy?
Does oral amiodarone treatment alter exercise hemodynamics and left ventricular relaxation in patients with hypertrophic cardiomyopathy?
Long-term amiodarone treatment in patients with hypertrophic cardiomyopathy worsens rest and exercise hemodynamics, likely due to a negative inotropic effect, without altering echocardiographic relaxation indexes.
No takes yet. Share an insight, caveat, or question.
Amiodarone was associated with worsened exercise hemodynamics in HCM; leaves open outcome impact and need for randomized trials.
Paulus et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: